Slow-growing verrucae are designed to avoid detection by the body’s immune system. Two-thirds of the time, one treatment works. The exposed lesion above the skin surface, primarily dead debris, makes it difficult to get to the active infection site. As a result, freezing the infected cells below the surface is difficult. Commonly, the lesion is debulked with over-the-counter wart treatments for a month. Next, use the CryoPen to freeze for 45-60 * seconds at a time. Permit the lesion to heal for 3 to 4 weeks, and then follow up. Re-freeze and re-check the lesion until you are confident that it is not re-growing again. However, if the condition returns, you should return as soon as possible to get the best results possible. In order to successfully treat a common wart, patient expectations and compliance are essential.